Different yes, but not that much quicker really. Unless you're on a really straight road, the 2.2 will handle better than the tubby and much closer to the VXR. Again, in a straight line the Zed will pass the 2.2, but on the twisty stuff the VX will be more than a match for it.
Then again, you'll be freezing your knackers off in the VX and constantly wondering what that new rattle is, whereas you'll be somewhat more relaxed in the 350
One of the best pax rides I've ever had was in a 2.2 with Nitrons and a set of throttle bodies round Bedford GT. Easily on a par with my stg2 VXR in terms of speed, both straight line and cornering. Truly an awesome car.